Axonal growth and pathfinding: from phenomena to molecules
نویسندگان
چکیده
منابع مشابه
Fernando de Castro Development Pathfinding and Cell Migration During CNS Chemotropic Molecules : Guides for Axonal
Int. Union Physiol. Sci./Am.Physiol. Soc.. ESSN: 1548-9221. Visit our website at http://www.the-aps.org/. December by the American Physiological Society, 9650 Rockville Pike, Bethesda MD 20814-3991. © 2003 physiological developments. It is published bimonthly in February, April, June, August, October, and (formerly published as News in Physiological Science) publishes brief review articles on m...
متن کاملChemotropic molecules: guides for axonal pathfinding and cell migration during CNS development.
Different molecules (netrins, semaphorins, slits) with chemotropic functions and their receptors (neogenin, DCC, neuropilins, plexins, robos) have been identified that guide axons during development of the nervous system to establish the complex pattern of connections among a large number of neurons. These molecules have been recently identified to play a role in cell migration of the central n...
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Precise patterning of axon guidance cue distribution is critical for nervous system development. Using a murine forward genetic screen for novel determinants of axon guidance, we identified B3gnt1 and ISPD as required for the glycosylation of dystroglycan in vivo. Analysis of B3gnt1, ISPD, and dystroglycan mutant mice revealed a critical role for glycosylated dystroglycan in the development of ...
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In the previous paper (Raper, J.A., M. Bastiani, and C.S. Goodman (1983) J. Neurosci. 3:20-30) we showed that the growth cones of two sibling neurons, the G and C cells, follow the same route in the developing grasshopper neuropil until they reach a stereotypic choice point. Here their growth cones diverge from each other as G turns and extends anteriorly and C turns and extends posteriorly. In...
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ژورنال
عنوان ژورنال: Cell and Tissue Research
سال: 1997
ISSN: 0302-766X,1432-0878
DOI: 10.1007/s004410050921